November 28, 2021

Vertigo Treatment Blog

Advancing the diagnosis and treatment of vertigo and balance disorders..


1 min read

Benzodiazepines, barbiturates, and sedative-hypnotics are central nervous system depressants that work by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA), resulting in anxiolytic (anti-anxiety), hypnotic (sleep-inducing), anticonvulsant, and muscle relaxant properties. This pharmacology lecture covers topics such as pathophysiology of anxiety and insomnia, role of GABA in the central nervous system, structure and function of GABA-A receptor, limbic system, mechanism of action and side effects of benzodiazepines, barbiturates, and non-benzodiazepine sedative-hypnotics. Drugs mentioned include; Alprazolam, Chlordiazepoxide, Clonazepam, Diazepam, Lorazepam, Temazepam, Pentobarbital, Phenobarbital, Secobarbital, Zolpidem, Zaleplon, and Eszopiclone.

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0:00 Intro
0:28 GABA and its receptors
2:18 Limbic system
3:34 Benzodiazepines
5:18 Barbiturates
6:57 Nonbenzodiazepine hypnotics



  1. I’m a researching parent and have a child with epilepsy. The company Sabril required me to sign a waiver for their drug Vigabatrin. I read that it was a permanent GABA inhibitor and found little else on the subject matter. Could you please do a presentation for how the drug Vigabatrin works on the brain 🧠? Also could you please explain what permanent GABA inhibitors do in other areas such as emotional effects and physical? Thank you 🙏 this information would be very appreciated.

  2. I suffered with sleeping disorders for more than 2 years and thought there seems to be no solution for me. Not until a psychological behavioral therapist offered this specific remedy , Sυnodoz Plan , Go ogle it ,. It assist me to understand science how we sleep. I`m at this moment resting easily again every night. Sleeping on the bed is a superb experience overnight..

  3. omg if this is how pharmacists are trained these days no wonder they are so incompetent. no mention of siezures? no mention of many uses in the e.r. like stopping siezures or serotinin syndrome? these do many more important things than treating 'anxiety'. everyone watching this should fail if they dont know those things.

  4. Zolpidem does actually have anti-anxyolitic properties, compared to, or even stronger than most benzodiazepines. But be careful with this drug, don't mix it with alcohol. It has an extremely rapid onset if action, puts you to sleep within a dozen minutes, but real hell begins after 3-4 hrs, when it stops working.

  5. just watched it after an one & half hour lecture & i swear that these 8 minutes have OVERSTRAINED in quality , THANKS MAN

  6. Fantastic, I have to prepare presentations for some mixed opioid agonist/antagonists and affinity issues to support my literature. Do you use Doodly or anything like that?

  7. Dr can answer me please. Brain regeneration and relaxation meditation everyday or mindfulness can relieve symptoms or shorten the duration of withdrawal benzodiazepines Thanks !!!

  8. Wow so it does affect cerebellum spine brainstem.
    Please tell me how would benzis or Zdrugs affect brainstem, cerrebellum and spine be affected if a person were on them for 40 yrs then removed too quickly causing all sorts of damage?

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